Smad 2/3 western blot
WebbPhospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) (D27F4) Rabbit mAb recognizes endogenous levels of Smad2 protein when phosphorylated at Ser465 and Ser467. This … WebbMonoclonal Antibody for studying Smad3 (Ser423/Ser425) phosphate/Smad2 (Ser465/Ser467) phosphate. Cited in 620 publications. Validated for Western Blotting. …
Smad 2/3 western blot
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WebbGalunisertib (TGF-β/Smad抑制剂) 5mg加入1.35ml DMSO，或者每3.69mg加入1ml DMSO，配制成10mM溶液。. SF7926-10mM用DMSO配制。. Galunisertib (LY2157299)是有效的TGFβ receptor I (TβRI)抑制剂，无细胞试验中IC50为56nM。. Phase 2/3。. LY2157299有效地抑制了TGFβ受体信号。. LY2157299抑制了HUVEC细胞中 ... Webb13 apr. 2024 · SM reduced relative protein and gene expression in mice peritoneal fibrosis (PF) by RT-qPCR and Western blotting respectively ( n = 6/group). a – d the mRNA expression of TGF-β1, Smad2, Smad3, Smad4, and smad7 in the peritoneal tissue. e Protein bands of TGF-β1, p-Smad2, Smad2, p-Smad3, Smad3, Smad4, Smad7, and GAPDH. f – l …
Webb26 apr. 2024 · Data are good. I used SMAD as my control of pSMAD/SMAD pathway. Cells were stimulated with TGF-b in starvation medium. Our research is focused on the SMAD …
WebbSMAD family member 2 antibody; SMAD, mothers against DPP homolog 2 antibody; SMAD2 antibody; SMAD2_HUMAN antibody; see all. Images. Western blot - Anti-Smad2 … WebbCurcumin reverses oxaliplatin resistance in human colorectal cancer via regulation of TGF-beta/Smad2/3 signaling pathway Jiahuan Yin,1 Li Wang,2 Yong Wang,1 Hailong Shen,1 Xiaojie Wang,1 Lei Wu11Department of General Surgery, Shanghai Luodian Hospital, Shanghai 202408, People’s Republic of China; 2Department of Gynaecology and …
Webb29 sep. 2024 · The global targeted disruption of the natriuretic peptide receptor-A (NPRA) gene (Npr1) in mice provokes hypertension and cardiovascular dysfunction. The objective of this study was to determine the mechanisms regulating the development of cardiac fibrosis and dysfunction in Npr1 mutant mice. Npr1 knockout (Npr1−/−, 0 …
Webb18 apr. 2024 · Phosphorylated Smad ( p Smad) 2/3 and phosphorylated adenosine monophosphate-activated protein kinase ( p AMPK) were then determined by Western blotting. Results TGF-β1 stimulation increased α-SMA and MMP-9 mRNA expression and protein production in nasal polyp fibroblasts. dusseldorf airport iataWebbMembers of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-β signals from the cell surface into the nucleus. … dusseldorf airport to oberhausenWebb23 maj 2024 · Similarly, western blot analyses (Fig 3C and 3D) show that SB counteracted the effect of TGF-ß1 restoring megalin protein levels. Furthermore, ... as seen in the … dv arrowhead\u0027sWebbSAA1 deficiency decreases cardiac fibrosis through inhibiting TGFβ/Smad signal pathway activation in mice after aortic banding. (A) Serum level of IL-6, IL-1β, TNFα from mice was detected using an ELISA. (B) Western blotting analysis of TGF-β, α-SMA, p-Smad2, and p-Smad3 and Smad7 proteins. GAPDH was used as a loading control. dv american visa lottery 2024WebbAn atomized and inhaled drug-loaded nanoparticle, an siRNA sequence group for treating pulmonary fibrosis, and a design method therefor. Specifically, an atomized and inhaled drug-loaded nanoparticle is provided, characterized in that said nanoparticle comprises: a biodegradable ampiphilic block copolymer and a cationic lipid compound, the molar ratio … dv arrowhead\\u0027sWebbSmad2 ubiquitously expressed transcription factor phosphorylated and activated by TGF-beta receptor-type kinases. Participates in a wide range of critical processes including … dusseldorf airport to bochum by trainWebbAnti-phospho-Smad3 (Ser423/425) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Smad3 (Ser423/425) also known as MAD Mothers against DPP homolog 3 & … dusseldorf airport lost and found